Wake County and Fuquay-Varina offers access to some of the best healthcare in the country. There are three major medical systems, including two teaching hospitals within 30 minutes of each other.

Founded in 1961 as the Memorial Hospital of Wake County, today its a three-hospital 919-bed private not-for-profit health system based in Raleigh. It's flagship campus includes North Carolina's first freestanding children's emergency department, and is designated a Level 1 trauma center by the North Carolina Office of Emergency Medical Services. Additionally, WakeMed has more than a dozen facilities located throughout Wake County.

Founded in 1894, UNC Rex Healthcare, a member of UNC Healthcare, is a private not-for-profit healthcare system. Rex Healthcare has multiple facilities around Wake County. UNC Healthcare and Rex have a total combined  and has a total of 1,463 beds at the various locations across the Triangle region.

Founded in 1998, Duke University Health System is 957-bed tertiary and quaternary-care hospital, consistently rated as one of the top hospitals in the United States. Additionally Duke Regional Hospital is an acute care facility with 369-beds.